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autism brain imaging data exchange release 1  (NeuroMark Genomics Inc)
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NeuroMark Genomics Inc autism brain imaging data exchange release 1
Results of study 2, which supports that SZ <t>and</t> <t>ASD</t> show common alterations in sFNC. (A): Mean sFNC pattern across all subjects for <t>ABIDEI.</t> (B) and (C): T-values of all sFNCs and T-values of the sFNCs passing the multiple comparisons correction (p < 0.05 with Bonferroni correction), obtained from two-sample t-tests of HC vs. ASD for ABIDEI. “BFN” denotes Bonferroni correction. (D): Mean sFNC strength of each group (ASD, SZ and HC) in the common impairments between SZ and ASD. For each commonly impaired sFNC, the averaged connectivity values in ASD patients of ABIDEI, SZ patients of FBIRN and MPRC, and HCs of the three datasets are shown, respectively. (E) and (F): The significant correlations (r and p values) between FNC measures and clinical symptoms, with p < 0.05. The T-value from testing group difference between HC and disorder by two-sample t -test is also included in each subfigure. Taking (F) for an instance, it shows the correlation between FNC measure (corresponding to IC 69 and IC 21) and ADOS score in ASD patients. The T-value of FNC measure from two-sample t -test between HC and ASD is also shown in the title part.
Autism Brain Imaging Data Exchange Release 1, supplied by NeuroMark Genomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Results of study 2, which supports that SZ and ASD show common alterations in sFNC. (A): Mean sFNC pattern across all subjects for ABIDEI. (B) and (C): T-values of all sFNCs and T-values of the sFNCs passing the multiple comparisons correction (p < 0.05 with Bonferroni correction), obtained from two-sample t-tests of HC vs. ASD for ABIDEI. “BFN” denotes Bonferroni correction. (D): Mean sFNC strength of each group (ASD, SZ and HC) in the common impairments between SZ and ASD. For each commonly impaired sFNC, the averaged connectivity values in ASD patients of ABIDEI, SZ patients of FBIRN and MPRC, and HCs of the three datasets are shown, respectively. (E) and (F): The significant correlations (r and p values) between FNC measures and clinical symptoms, with p < 0.05. The T-value from testing group difference between HC and disorder by two-sample t -test is also included in each subfigure. Taking (F) for an instance, it shows the correlation between FNC measure (corresponding to IC 69 and IC 21) and ADOS score in ASD patients. The T-value of FNC measure from two-sample t -test between HC and ASD is also shown in the title part.

Journal: NeuroImage : Clinical

Article Title: NeuroMark: An automated and adaptive ICA based pipeline to identify reproducible fMRI markers of brain disorders

doi: 10.1016/j.nicl.2020.102375

Figure Lengend Snippet: Results of study 2, which supports that SZ and ASD show common alterations in sFNC. (A): Mean sFNC pattern across all subjects for ABIDEI. (B) and (C): T-values of all sFNCs and T-values of the sFNCs passing the multiple comparisons correction (p < 0.05 with Bonferroni correction), obtained from two-sample t-tests of HC vs. ASD for ABIDEI. “BFN” denotes Bonferroni correction. (D): Mean sFNC strength of each group (ASD, SZ and HC) in the common impairments between SZ and ASD. For each commonly impaired sFNC, the averaged connectivity values in ASD patients of ABIDEI, SZ patients of FBIRN and MPRC, and HCs of the three datasets are shown, respectively. (E) and (F): The significant correlations (r and p values) between FNC measures and clinical symptoms, with p < 0.05. The T-value from testing group difference between HC and disorder by two-sample t -test is also included in each subfigure. Taking (F) for an instance, it shows the correlation between FNC measure (corresponding to IC 69 and IC 21) and ADOS score in ASD patients. The T-value of FNC measure from two-sample t -test between HC and ASD is also shown in the title part.

Article Snippet: In study 2, we identified the functional changes in ASD using the release 1 of Autism Brain Imaging Data Exchange (ABIDEI) data, and then linked the results to study 1, aiming to show the ability of NeuroMark in the cross-disorder comparison.

Techniques: